Last update
10/5/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
USERS' SCORE
Good
Based on 18 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Oregano Oil (Origanum vulgare) min. 55% Carvacrol)
0.2 ml / 181 mg
**
Ginger Oil (Zingiber officinale)
0.02 ml / 17.6 mg
**
Fennel Oil (Foeniculum vulgare)
0.02 ml / 19.3 mg
**
Top Medical Research Studies
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
Most Useful Reviews
9
Effective for gut issues
15 people found this helpful
Fantastic natural product! I've an autoimmune condition that occasionally affects my gut and leads to SIBO (small intestine bacterial overgrowth). Rather than relying on anti-fungal medications, this natural oregano oil restores my health quickly! I commence with two capsules daily for a week, followed by one daily for the subsequent week or two.
Read More
9
Effective for allergies
6 people found this helpful
I order oregano oil to manage my seasonal allergies. It works better for me than allergy shots or other medications; I can breathe freely. While most days I only take one softgel, two during peak allergy periods, the improvement has been remarkable.
Read More
9
Symptoms alleviated
2 people found this helpful
I received this product just a few days after ordering via DHL. It seems to work well; I took it while feeling very unsettled and experiencing chills. After just 1-2 days, all symptoms had disappeared.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.2
- All Researches
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Read More
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
Read More
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for gut issues
15 people found this helpful
Fantastic natural product! I've an autoimmune condition that occasionally affects my gut and leads to SIBO (small intestine bacterial overgrowth). Rather than relying on anti-fungal medications, this natural oregano oil restores my health quickly! I commence with two capsules daily for a week, followed by one daily for the subsequent week or two.
Read More
9
Effective for allergies
6 people found this helpful
I order oregano oil to manage my seasonal allergies. It works better for me than allergy shots or other medications; I can breathe freely. While most days I only take one softgel, two during peak allergy periods, the improvement has been remarkable.
Read More
9
Symptoms alleviated
2 people found this helpful
I received this product just a few days after ordering via DHL. It seems to work well; I took it while feeling very unsettled and experiencing chills. After just 1-2 days, all symptoms had disappeared.
Read More
7.5
Candida management aid
2 people found this helpful
Can't be without it! This product helped manage my candida effectively. I highly recommend it; however, please avoid taking it on an empty stomach. I've ordered another bottle.
Read More
7.5
Reduced cravings
31 people found this helpful
I am ordering oregano oil again as part of my treatment for Candida. Two years ago, I successfully reduced my weight from 80 kg to 74 kg and experienced a complete loss of sweet cravings. I believe that oregano oil, combined with other supplements, will yield similar results again.
Read More
Frequently Asked Questions
9
Symptoms alleviated
2 people found this helpful
I received this product just a few days after ordering via DHL. It seems to work well; I took it while feeling very unsettled and experiencing chills. After just 1-2 days, all symptoms had disappeared.
9
Effective for gut issues
15 people found this helpful
Fantastic natural product! I've an autoimmune condition that occasionally affects my gut and leads to SIBO (small intestine bacterial overgrowth). Rather than relying on anti-fungal medications, this natural oregano oil restores my health quickly! I commence with two capsules daily for a week, followed by one daily for the subsequent week or two.
6
Cleared strep symptoms
1 people found this helpful
I ordered oregano oil to address strep throat, and after 1.5 months, I haven't experienced any symptoms since. Additionally, I noticed the added benefit of my acne disappearing, which was quite a surprise.
9
Effective for allergies
6 people found this helpful
I order oregano oil to manage my seasonal allergies. It works better for me than allergy shots or other medications; I can breathe freely. While most days I only take one softgel, two during peak allergy periods, the improvement has been remarkable.
7.5
Works effectively
3 people found this helpful
I ordered this supplement to complement other products, like grapefruit seed extract for killing Candida, and found it worked remarkably well.
7.5
Reduced cravings
31 people found this helpful
I am ordering oregano oil again as part of my treatment for Candida. Two years ago, I successfully reduced my weight from 80 kg to 74 kg and experienced a complete loss of sweet cravings. I believe that oregano oil, combined with other supplements, will yield similar results again.
7.5
Shortens illness duration
1 people found this helpful
Oregano oil is effective for colds and viruses, significantly reducing the duration of illness. I appreciate its value and will certainly reorder. I often take it alongside garlic and olive leaf for added benefits.
7.5
Effective against CIGR/SIBR
6 people found this helpful
A very good preparation for combating CIGR/SIBR. It's best used in conjunction with similar functional products (like nim, monolaurin, or ant tree bark). It's important to introduce sorbents during the intake to eliminate dead pathogens. It’s easy to consume, and I followed the instructions for use. A very effective product!
7.5
Strong recommendation
6 people found this helpful
If you are suffering from SEBO or intestinal issues caused by harmful bacteria, I highly recommend taking this. Take one pill daily before a substantial meal, as it’s potent. Note that harmful bacteria overgrowth has a strong odour, so avoid ordering it in the summer.
7.5
Candida management aid
2 people found this helpful
Can't be without it! This product helped manage my candida effectively. I highly recommend it; however, please avoid taking it on an empty stomach. I've ordered another bottle.
9
We explored the potential of Origanum vulgare L. ssp. hirtum, commonly known as Greek oregano, in the realm of autoimmune disorders, particularly type 1 diabetes (T1D). This study specifically looked at how an ethyl acetate extract of oregano (EAO) could influence the development of T1D in mice.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
To conduct the research, researchers induced type 1 diabetes in male C57BL/6 mice using multiple low doses of streptozotocin. They then treated these mice with EAO over ten days. Our findings revealed that EAO not only reduced the incidence of diabetes but also helped preserve pancreatic islets—critical for insulin production.
The results were promising as we observed significant immunomodulatory effects from the oregano extract. In vitro tests indicated that EAO suppressed the activation of immune cells, particularly macrophages and T lymphocytes. Furthermore, it appeared to decrease the levels of certain inflammatory T cell populations and their associated transcription factors, which play a role in promoting inflammation.
These discoveries suggest that oregano extract could potentially serve as a therapeutic option for managing type 1 diabetes by targeting the autoimmune responses involved in the disease. Overall, this study highlights an exciting avenue for plant-based treatments in diabetes management.
9
We explored the potential benefits of Oregano, specifically its methanolic extract, for treating type 1 diabetes (T1D), an autoimmune condition characterized by the destruction of insulin-producing β-cells in the pancreas. In our study, we investigated this by using a group of mice that were subjected to a diabetes-inducing treatment with streptozotocin.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
We found that the methanolic extract of Oregano, also known as MOE, showed promising results in reducing diabetes incidence compared to the aqueous extract. MOE not only helped to maintain normal insulin secretion but also acted as a powerful antioxidant, reducing harmful reactive oxygen and nitrogen species in the body. This is significant since oxidative stress can worsen the state of autoimmune diseases.
Additionally, our research revealed that MOE played a role in modulating the immune response. It reduced inflammation by affecting T helper cells, which are crucial in the immune response—but not in a way that would hurt the body’s defenses. Importantly, MOE seemed to protect the pancreatic β-cells from programmed cell death, a critical factor in the progression of diabetes.
While one prominent compound in MOE, rosmarinic acid, offered only partial protection, the overall findings suggest that multiple components in the extract contribute to its beneficial effects. Overall, it appears that Oregano's properties as an antioxidant, anti-inflammatory, and anti-apoptotic agent may help in managing T1D.
9.5
Oregano component improves immune regulation
We explored how a natural component found in oregano, known as carvacrol, can influence the body's immune response, particularly in the context of autoimmune arthritis. The study aimed to see if boosting the levels of heat-shock proteins like Hsp70 could help in regulating inflammation caused by the immune system.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
Through both laboratory experiments and tests in mice, we found that carvacrol significantly increased the expression of Hsp70, which in turn enhanced T cell responses. This led to improved recognition of Hsp70 by T cells, suggesting that the immune system was effectively responding to this stress protein.
Furthermore, our results showed that carvacrol administration not only promoted the growth of protective T cells but also notably suppressed the symptoms of experimental arthritis. In fact, T cells taken from mice that had consumed carvacrol were capable of transferring this protective effect to other mice.
Overall, our findings indicate that dietary components like carvacrol can play a vital role in regulating immune responses, ultimately helping to manage inflammatory diseases like autoimmune arthritis.
References
- Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, et al. Ethyl Acetate Extract of Origanum vulgare L. ssp. hirtum Prevents Streptozotocin-Induced Diabetes in C57BL/6 Mice. J Food Sci. 2016;81:H1846. 10.1111/1750-3841.13333
- Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, et al. Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity. Br J Nutr. 2015;113:770. 10.1017/S0007114514004048
- Wieten L, van der Zee R, Spiering R, Wagenaar-Hilbers J, van Kooten P, et al. A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis. Arthritis Rheum. 2010;62:1026. 10.1002/art.27344
